The tissue core samples are sent to a laboratory for analysis by a pathologist.
If cancer is present, the pathologist will assign a grade
for each of the tissue cores, (which will result in a total grade for the cancer).
The individual tissue core grade refers to the cancer's appearance and indicates how quickly a cancer is growing.
Pathologists grade prostate cancer according to the Gleason score, which assigns a grade (1 to 5) based on how the cancerous cells look compared to normal prostate cells.
Grade 5. The cells do not look like normal prostate cells. They appear to be scattered haphazardly throughout the prostate.
- His biopsy consisted of 12 tissue cores, all 12 were 100% cancerous.
- 8 cores were grade 5 and 4 cores were grade 4 (= a Gleason score of 9, indicating a very aggressive cancer).